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The creation and properties of the phantoms of biological tissue containing nanoparticles

Abstract

The creation and properties of the phantoms of biological tissue containing nanoparticles

Mohammed A.H.M., Ustalkov S.O., Sagaidachnaya E.A., Kochubey V.I., Skaptsov A.A.

Incoming article date: 29.03.2019

Phantoms are an imitation of biological tissue. With the help of phantoms, it is possible to simulate the propagation of light in biological tissue. During any biophysical experiments there is a need for the constancy of the initial conditions of the experiment. The use of solid phantoms that do not degrade over time and under the influence of external factors is the Foundation for reliable results and repeatability of the experiment. The creation of phantoms of biological tissue containing fluorescent nanoparticles or nanoparticles with high absorption, and which correspond to specific mechanical or optical properties, is an urgent task. The paper describes the development, fabrication and characterization of solid tissue phantoms containing gold and upconversion nanoparticles. Optical and mechanical properties of phantoms are studied. The temperature range suitable for the use of samples as phantoms of biological tissue for laser thermolysis problems was revealed.

Keywords: phantom, gold nanorods, luminescence, quantum dots, thermogravimetric analysis